Ozempic and Your Smile: What South Africans Need to Know About Its Dental Side Effects

Puzzle letters spelling "Ozempic" on a marble background, with other scattered tiles suggesting themes of health and medication.

Is your weight-loss journey affecting your smile? Ozempic, the popular medication for managing type 2 diabetes and aiding weight loss, has taken South Africa by storm. From Joburg’s bustling clinics to Cape Town’s health-conscious suburbs, many are turning to this GLP-1 drug to shed kilos and control blood sugar. But there’s a catch—dentists are noticing a rise in oral health issues linked to Ozempic, dubbed “Ozempic teeth” on social media. So, what’s happening to your mouth, and how can you protect your smile? Let’s dive into the dental side effects of Ozempic and why they matter for South Africans.

What’s Ozempic, and Why the Hype?

Ozempic (semaglutide) is an injectable medication originally designed for type 2 diabetes. It mimics a hormone called GLP-1, which regulates blood sugar and slows digestion, helping you feel full longer. This appetite suppression has made it a go-to for weight loss, even for those without diabetes. In South Africa, where obesity rates are climbing (over 30% of adults are obese, according to the WHO), Ozempic’s appeal is clear. But while it’s transforming waistlines, it’s also raising red flags for oral health.

How Ozempic Affects Your Teeth and Gums

Ozempic’s side effects can create a perfect storm for your mouth. Here’s how it’s showing up in dental chairs across South Africa:

1. Dry Mouth (Xerostomia)

One of the most common complaints is dry mouth, where saliva production drops. Saliva is your mouth’s natural defender—it washes away bacteria, neutralises acids, and strengthens enamel with minerals. Without it, you’re left with a sticky, dry feeling, bad breath, and a higher risk of cavities and gum disease. Ozempic’s slowing of digestion may reduce thirst signals, leading to dehydration, which worsens dry mouth. In South Africa’s hot climate, this is a double whammy.

2. Acid Reflux and Enamel Erosion

Ozempic slows stomach emptying, which can cause acid reflux or nausea. When stomach acid reaches your mouth—whether from reflux or vomiting—it erodes enamel, making teeth sensitive, discoloured, or prone to decay. This is especially concerning for South Africans who may already battle acid-heavy diets (think cool drinks or citrus fruits).

3. Gum Inflammation and Disease

Some Ozempic users report bleeding or swollen gums, signs of gingivitis that can progress to periodontitis if ignored. The drug’s impact on the body’s inflammation response and oral microbiome may play a role. For those with diabetes, already at higher risk for gum disease, this is a critical issue. In South Africa, where gum disease is a leading cause of tooth loss, this side effect hits hard.

4. Bad Breath (Halitosis)

Bad breath is another frequent complaint, tied to dry mouth, acid reflux, or even ketosis—a state where Ozempic’s fat-burning process produces ketones, giving breath a distinct odor. This can be socially awkward, especially in close-knit South African communities where first impressions matter.

5. Diet Changes and Nutrient Deficiencies

Ozempic’s appetite suppression can lead to smaller meals or softer, processed foods to manage nausea. This might mean missing out on calcium, vitamin D, or vitamin C—key for strong teeth and gums. In South Africa, where dietary staples like pap or bread can be carb-heavy, these shifts can increase cavity risk if oral hygiene slips.

Why This Matters in South Africa

South Africa’s healthcare landscape makes these side effects especially relevant. Dental care access is limited—only 25% of dentists work in the public sector, serving 84-90% of the population, according to the South African Dental Association. Rural areas like Limpopo or the Eastern Cape often lack nearby clinics, and private care can cost thousands of rands. Add in economic pressures (unemployment was 32.9% in 2024) and cultural habits of delaying dental visits until pain strikes, and small issues like cavities or gingivitis can become serious. For Ozempic users, these challenges amplify the need to stay proactive.

The social media buzz around “Ozempic teeth” also hits home in South Africa, where Instagram and TikTok shape beauty standards from Sandton to Soweto. Seeing influencers flaunt perfect smiles can push users to overlook risks, but the reality is that neglecting these side effects could lead to costly dental fixes down the line.

Are You Seeing These Signs?

If you’re on Ozempic, watch for these oral health red flags:

• Dry, sticky mouth or constant thirst.

• Bad breath that lingers despite brushing.

• Sensitive, bleeding, or swollen gums.

• New cavities or tooth sensitivity.

• Metallic or bitter taste changes (“Ozempic tongue”).

• Jaw pain or cracked teeth from stress-related grinding.

If any ring a bell, don’t wait—act now to protect your smile.

Protecting Your Smile on Ozempic

You don’t have to choose between your health goals and your teeth. Here’s how to keep your smile shining in 2025:

• Stay Hydrated: Sip water all day, especially in South Africa’s heat. Carry a water bottle and aim for 2-3 litres daily to combat dry mouth.

• Boost Saliva: Chew sugar-free gum (xylitol is best) or suck on sugar-free lozenges to stimulate saliva flow. This helps neutralise acids and clear bacteria.

• Brush Smart: Use fluoride toothpaste twice daily and floss daily. After reflux or vomiting, rinse with water or a baking soda solution before brushing to protect enamel.

• Eat Balanced: Even with reduced appetite, include calcium-rich foods (amasi, milk, leafy greens) and vitamin-packed fruits to support teeth and gums. Avoid sugary snacks or acidic drinks like cool drinks.

• See Your Dentist: Book regular check-ups—twice a year if possible. Tell your dentist you’re on Ozempic so they can monitor for issues like gum disease or enamel erosion.

• Manage Reflux: If nausea or acid reflux persists, talk to your doctor. They may adjust your dose or prescribe meds to reduce stomach acid.

A young man refreshes himself under the warm sun, enjoying a drink of water from a bottle, set against a serene outdoor backdrop.

The Bigger Picture: Is It Worth It?

Ozempic offers life-changing benefits for diabetes control and weight loss, but it’s not without trade-offs. The term “Ozempic teeth” may not be an official diagnosis, but the anecdotal reports are piling up—dentists in South Africa and beyond are seeing more patients with dry mouth, bad breath, and gum issues. While direct scientific evidence is still emerging, the link between Ozempic’s side effects (like dry mouth and acid reflux) and oral health risks is clear.

In South Africa, where dental care can be a luxury, prevention is your best bet. Don’t let “Ozempic teeth” catch you off guard—small habits like hydration and regular dental visits can keep your smile strong while you reap the drug’s benefits.

Conclusion: Your Smile, Your Health

Ozempic is a game-changer for many South Africans, but its effects on your mouth are a reminder that health is interconnected. From dry mouth to gum inflammation, the remnants of this medication can linger in your smile if you’re not careful. In a country where dental care access is uneven, staying proactive is non-negotiable. At Smilez Dental Surgery, we’re here to help you navigate these challenges. Tell your dentist about Ozempic, stick to good oral hygiene, and keep sipping that water. Book your check-up today—your smile deserves to shine as bright as your health goals!